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Ondansetron injection, commonly known by brand names like Zofran, is a powerful antiemetic medication used to prevent and treat severe nausea and vomiting. It is a selective serotonin 5-HT$_3$ receptor antagonist. This injection is administered either intramuscularly (IM) or intravenously (IV) and is particularly effective for nausea and vomiting caused by chemotherapy, radiation therapy, and surgery.

The mechanism of action of ondansetron involves blocking the action of serotonin, a natural substance in the body that can trigger the vomiting reflex. Serotonin 5-HT$_3$ receptors are located in both the central nervous system (specifically the chemoreceptor trigger zone in the brain) and peripherally on the vagus nerve terminals in the gastrointestinal tract. By blocking these receptors, ondansetron prevents the signals that cause nausea and vomiting from reaching the brain, thereby providing its antiemetic effect.

The administration of ondansetron injection is carefully managed by healthcare professionals. The dosage and timing depend on the specific medical condition it's being used for. For instance, in cases of chemotherapy-induced nausea, it is typically given before the start of the treatment. For post-operative nausea, it is administered shortly before or during surgery, or afterwards if necessary.

Symptoms of Infections DEEPTRON Injection Treats

Ondansetron injection does not treat infections. Its sole purpose is to treat the symptoms of nausea and vomiting. While nausea and vomiting can be symptoms of an infection, ondansetron does not have any antimicrobial properties and will not cure the underlying infection. It only provides relief from the associated feeling of sickness.

Common Symptoms Include:

  • Nausea and vomiting associated with cancer treatments:
  • This is its most common use, particularly for patients undergoing chemotherapy and radiation therapy.
  • Postoperative nausea and vomiting:
  • It is often administered to patients before, during, or after surgery to prevent them from feeling sick.
  • An infection would require a specific treatment, such as antibiotics for a bacterial infection or antivirals for a viral infection.

Note:

The symptoms listed above are for general informational purposes only and do not constitute medical advice or a diagnosis. Always consult a qualified healthcare professional before starting any treatment. Self-medication based on these symptoms can be harmful. We are not responsible for any misuse or consequences resulting from such actions.

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Medical Disclaimer:
The content on this website is for general information only and not a substitute for medical advice. Do not use any medication or product listed on this site without consulting a qualified doctor. Sumandeep Lifesciences LLP is not responsible for any misuse, adverse effects, or outcomes arising from self-medication.

Uses of DEEPTRON Injection:

  • To prevent and treat chemotherapy-induced nausea and vomiting (CINV):It is a standard and highly effective treatment for patients undergoing cancer chemotherapy, which often causes severe nausea and vomiting. The injection is typically given before the start of chemotherapy to prevent these symptoms.
  • To prevent and treat radiation-induced nausea and vomiting: Similar to chemotherapy, radiation therapy can also cause significant nausea and vomiting, and ondansetron is used to manage this side effect.
  • To prevent and treat postoperative nausea and vomiting (PONV):Ondansetron is frequently given to patients before, during, or after surgery to prevent them from feeling sick, which can be a common side effect of anesthesia.

Medicine Details


  • Do not use if solution is not clear or having suspended matter / particles and ask for replacement.

  • Ondansetron Hydrochloride IP Eq. to Ondansetron: 2mg
  • Methylparaben IP (As preservative): 0.1% w/v
  • Propylparaben IP (As preservative): 0.01% w/v
  • Sodium Metabisulphite IP (As preservative): 0.1% w/v
  • Water for Injection IP: q.s.

  • Store in a cool, dry & dark place.
  • Protect from direct sunlight & moisture.
  • Store below 25°C.

  • As directed by the physician.
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